PATH-05. A CASE OF PILOCYTIC ASTROCYTOMA HARBORING THE FGFR1 GENE MUTATION WITH A PREDOMINANT OLIGODENDROGLIOMA-LIKE COMPONENT
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DOI: 10.1093/neuonc/noaa222.641
Abstract: Abstract Pilocytic astrocytomas rarely present with oligodendroglioma-like morphological features, which gives rise to a diagnostic challenge. In this report we present a case of pilocytic astrocytoma harboring the FGFR1 mutation, accompanied with a predominant oligodendroglioma-like… read more here.
Keywords: pilocytic astrocytoma; oligodendroglioma like; like component; oligodendroglioma ... See more keywords
Multicenter phase II study of temozolomide and myeloablative chemotherapy with autologous stem cell transplant for newly diagnosed anaplastic oligodendroglioma
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DOI: 10.1093/neuonc/nox086
Abstract: Background Anaplastic oligodendroglioma (AO) and anaplastic oligoastrocytoma (AOA) are chemotherapy-sensitive tumors with prolonged survival after radiochemotherapy. We report a prospective trial using induction temozolomide (TMZ) followed by myeloablative high-dose chemotherapy (HDC) with autologous stem-cell transplant… read more here.
Keywords: chemotherapy; anaplastic oligodendroglioma; oligodendroglioma; stem cell ... See more keywords
NIMG-63. LONGITUDINAL ANALYSIS OF OLIGODENDROGLIOMA GROWTH PATTERN REVEALED SPATIAL HETEROGENEITY AND DIVERSE TREATMENT RESPONSE
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DOI: 10.1093/neuonc/noz175.732
Abstract: Oligodendroglioma are defined by a distinct molecular phenotype marked by 1p19q co-deletion and simultaneous presence of an IDH1/2 mutation. These tumors showed a favorable clinical course and long-term survival of around 15 years. Due to… read more here.
Keywords: response; growth pattern; analysis; oligodendroglioma ... See more keywords
Prolonged benefit to pembrolizumab in anaplastic oligodendroglioma patient with mismatch repair deficiency: a case report.
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DOI: 10.1097/cad.0000000000001011
Abstract: High-grade gliomas, including anaplastic oligodendroglioma, represent the most common malignant neoplasms of the central nervous system in the adult. The standard treatment of anaplastic oligodendroglioma consists of maximum surgical resection, radiotherapy and subsequent chemotherapy. Despite… read more here.
Keywords: mismatch repair; oligodendroglioma; anaplastic oligodendroglioma; repair deficiency ... See more keywords
PI3K/AKT/mTOR Pathway Alterations Promote Malignant Progression and Xenograft Formation in Oligodendroglial Tumors
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DOI: 10.1158/1078-0432.ccr-18-4144
Abstract: Purpose: Oligodendroglioma has a relatively favorable prognosis, however, often undergoes malignant progression. We hypothesized that preclinical models of oligodendroglioma could facilitate identification of therapeutic targets in progressive oligodendroglioma. We established multiple oligodendroglioma xenografts to determine… read more here.
Keywords: oligodendroglioma; mtor pathway; pi3k akt; akt mtor ... See more keywords
Prognosis of Oligodendroglioma Patients Stratified by Age: A SEER Population-Based Analysis
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DOI: 10.2147/ijgm.s337227
Abstract: Purpose Glioma may affect patients of any age. So far, only a limited number of big data studies have been conducted concerning oligodendroglioma (OG) in diverse age groups. This study evaluated the risk factors for… read more here.
Keywords: age groups; risk; age; seer ... See more keywords
Challenges of imaging interpretation to predict oligodendroglioma grade: a report from the Neuro-Oncology Branch
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DOI: 10.2217/cns-2021-0005
Abstract: Background: To illustrate challenges of imaging interpretation in patients with oligodendroglioma seen at a referral center and evaluate interrater reliability. Methods: Two neuro-oncologists reviewed diagnostic preradiation MRIs of oligodendroglioma patients; interrater reliability was calculated with… read more here.
Keywords: oncology; oligodendroglioma; imaging interpretation; challenges imaging ... See more keywords
Oligodendroglioma resection: a Surveillance, Epidemiology, and End Results (SEER) analysis.
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DOI: 10.3171/2016.11.jns161974
Abstract: OBJECTIVE The available evidence suggests that the clinical benefits of extended resection are limited for chemosensitive tumors, such as primary CNS lymphoma. Oligodendroglioma is generally believed to be more sensitive to chemotherapy than astrocytoma of… read more here.
Keywords: analysis; surveillance epidemiology; gtr; oligodendroglioma ... See more keywords
Primary Leptomeningeal Oligodendroglioma, IDH-Mutant, 1p/19q-Codeleted
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DOI: 10.3389/fneur.2018.00700
Abstract: We present a case of a 43-year-old woman with a history of headaches and blurry vision. Ophthalmologic examination identified papilledema. MR imaging demonstrated a right parietal region mass with patchy areas of contrast enhancement and… read more here.
Keywords: oligodendroglioma idh; leptomeningeal oligodendroglioma; idh mutant; oligodendroglioma ... See more keywords
Vasculogenic Mimicry Formation Predicts Tumor Progression in Oligodendroglioma
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DOI: 10.3389/pore.2021.1609844
Abstract: Vasculogenic mimicry (VM) has been identified as an important vasculogenic mechanism in malignant tumors, but little is known about its clinical meanings and mechanisms in oligodendroglioma. In this study, VM-positive cases were detected in 28… read more here.
Keywords: tumor progression; vasculogenic mimicry; formation; oligodendroglioma ... See more keywords
Determination of genetic aberrations and novel transcripts involved in the pathogenesis of oligodendroglioma using array comparative genomic hybridization and next generation sequencing
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DOI: 10.3892/ol.2018.9811
Abstract: The aim of the present study was to determine the genetic aberrations and novel transcripts, particularly the fusion transcripts, involved in the pathogenesis of low-grade and anaplastic oligodendroglioma. In the present study, tissue samples were… read more here.
Keywords: genetic aberrations; genomic hybridization; oligodendroglioma; aberrations novel ... See more keywords