Sticholysin I–II oligomerization in the absence of membranes
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14326
Abstract: Sticholysins are pore‐forming toxins produced by the sea anemone Stichodactyla helianthus. When they encounter a sphingomyelin‐containing membrane, these proteins bind to it and oligomerize, a process that ends in pore formation. Mounting evidence indicates that StnII… read more here.
Keywords: oligomerization; oligomerization absence; absence membranes; membrane ... See more keywords
Removal of a consensus proline is not sufficient to allow tetratricopeptide repeat oligomerization
Sign Up to like & getrecommendations! Published in 2017 at "Protein Science"
DOI: 10.1002/pro.3234
Abstract: Tetratricopeptide repeat (TPR) domains are ubiquitous protein interaction domains that adopt a modular antiparallel array of α‐helices. The TPR fold typically adopts a monomeric state, and consensus TPRs sequences successfully fold into the expected monomeric… read more here.
Keywords: tetratricopeptide repeat; tpr; consensus proline; consensus ... See more keywords
Dissecting the behaviour of β‐amyloid peptide variants during oligomerization and fibrillation
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Peptide Science"
DOI: 10.1002/psc.3028
Abstract: The oligomerization and fibrillation of β‐amyloid (Aβ) peptides are important events in the pathogenesis of Alzheimer's disease. However, the motifs within the Aβ sequence that contribute to oligomerization and fibrillation and the complex interplay among… read more here.
Keywords: peptide; dissecting behaviour; behaviour amyloid; oligomerization fibrillation ... See more keywords
Protective effects of trehalose against Mn‐induced α‐synuclein oligomerization in mice: Involvement of oxidative stress and autophagy
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Toxicology"
DOI: 10.1002/tox.22842
Abstract: Overexposure to manganese (Mn) is widely known to induce alpha‐synuclein (α‐Syn) oligomerization, which has been attributed to the oxidative damage of α‐Syn protein. Trehalose has been shown to induce autophagy and serve as a chemical… read more here.
Keywords: syn oligomerization; stress autophagy; damage; oligomerization ... See more keywords
Evidence for different in vitro oligomerization behaviors of synthetic hIAPP obtained from different sources
Sign Up to like & getrecommendations! Published in 2020 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-020-02560-5
Abstract: Type 2 diabetes is characterized by the aggregation of human islet amyloid polypeptide (hIAPP), from monomer to amyloid deposits that are made of insoluble fibrils. Discrepancies concerning the nature of formed species or oligomerization kinetics… read more here.
Keywords: different sources; vitro oligomerization; evidence different; hiapp ... See more keywords
A theoretical study on La-activated bicyclo-oligomerization of acetylene to form naphthalene in gas phase using density functional theory (DFT)
Sign Up to like & getrecommendations! Published in 2017 at "Structural Chemistry"
DOI: 10.1007/s11224-017-1016-x
Abstract: In a recent experimental research, the formation of naphthalene has been demonstrated by La-mediated acetylene bicyclo-oligomerization in the gas phase, and this is the first report of metal-activated acetylene bicyclo-oligomerization to form the naphthalene. In… read more here.
Keywords: bicyclo oligomerization; acetylene; form naphthalene; reaction ... See more keywords
Geometric isomerism effect on catalytic activities of bis(oxalato)diaquochromates(III) for 2-chloroallyl alcohol oligomerization
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Chemical Sciences"
DOI: 10.1007/s12039-018-1515-3
Abstract: AbstractThe cis- and trans-potassium bis(oxalato)diaquochromates(III) have been studied towards their catalytic activity for the 2-chloroallyl alcohol oligomerization. The geometric isomerism effect on the oligomerization products under mild reaction conditions has been investigated. The molecular masses… read more here.
Keywords: hbox hbox; hbox; oxalato diaquochromates; oligomerization ... See more keywords
Computational prediction and redesign of aberrant protein oligomerization.
Sign Up to like & getrecommendations! Published in 2020 at "Progress in molecular biology and translational science"
DOI: 10.1016/bs.pmbts.2019.11.002
Abstract: Non-native intermolecular contacts often lead to aberrant protein oligomerization and aggregation. This phenomenon is behind the onset of several human disorders and is a bottleneck for the production of proteins of biotechnological interest. Intrinsically disordered… read more here.
Keywords: aggregation; aberrant protein; protein oligomerization; computational prediction ... See more keywords
Ethylene oligomerization on nickel catalysts on a solid acid support: From New mechanistic insights to tunable bifunctionality
Sign Up to like & getrecommendations! Published in 2021 at "Applied Catalysis A: General"
DOI: 10.1016/j.apcata.2021.118296
Abstract: Abstract Light alkene oligomerization on heterogeneous acidic catalysts is widely and successfully used in current commercial processes. However, ethylene oligomerization remains inefficient due to ethylene’s inability to form reaction intermediates to a sufficient extent on… read more here.
Keywords: oligomerization; ethylene oligomerization; support; oligomerization nickel ... See more keywords
Dysregulated autophagy is linked to BAX oligomerization and subsequent cytochrome c release in 6-hydroxydopmaine-treated neuronal cells.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.02.045
Abstract: Autophagy and apoptosis are essential physiological pathways that are required to maintain cellular homeostasis. Therefore, it is suggested that dysregulation in both pathways is linked to several disease states. Moreover, the crosstalk between autophagy and… read more here.
Keywords: apoptosis; dysregulated autophagy; bax oligomerization; oligomerization ... See more keywords
Ph-Induced Oligomerization of the Voltage Dependent Anion Channel
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.1018
Abstract: The Voltage-Dependent Anion Channel (VDAC) is the most abundant protein in the outer mitochondrial membrane facilitating the passage of ions and metabolites between the cytoplasm and the intermembrane space. In addition to its critical role… read more here.
Keywords: dependent anion; anion channel; microscopy; induced oligomerization ... See more keywords