Inhibition of alpha-synuclein aggregation by AM17, a synthetic resveratrol derivative.
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DOI: 10.1016/j.bbrc.2021.08.049
Abstract: Parkinson's disease (PD) is linked to the aberrant self-assembly of the amyloid protein, α-synuclein (αS), where αS monomers aggregate to form oligomers and fibrils. Out of the three conformers, αS oligomers are the major toxic… read more here.
Keywords: synuclein aggregation; aggregation; resveratrol; inhibition alpha ... See more keywords