Computational Design of Multiplex Oligonucleotide-Based Assays.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0822-7_2
Abstract: The success of any oligonucleotide-based experiment strongly depends on the accurate design of the components. Oli2go is a user-friendly web tool that provides efficient multiplex oligonucleotide design including specificity and primer dimer checks. Its fully… read more here.
Keywords: computational design; design multiplex; multiplex oligonucleotide; based assays ... See more keywords
The development of peptide- and oligonucleotide-based drugs to prevent the formation of abnormal tau in tauopathies
Sign Up to like & getrecommendations! Published in 2023 at "Expert Opinion on Drug Discovery"
DOI: 10.1080/17460441.2023.2200245
Abstract: ABSTRACT Introduction Tauopathies represent clinicopathological entities with increased and abnormal glial and/or neuronal inclusions of tau, a microtubule-binding protein. Antisense oligonucleotides (ASOs) are a promising therapeutic approach for treating tauopathies as they can target tau… read more here.
Keywords: tau; peptide oligonucleotide; expression; development peptide ... See more keywords