Prediction of shorter oligonucleotide sequences recognizing aflatoxin M1
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DOI: 10.1002/bab.1586
Abstract: Aflatoxin M1 (AFM1) is present in milk of lactating animals fed on aflatoxin B1 contaminated feeds. Aptamers are new emerging ligand molecules and can be employed in assay protocols. Shorter aptamers have several advantages. Untruncated… read more here.
Keywords: prediction shorter; reported aptamer; truncated aptamers; shorter oligonucleotide ... See more keywords
Natural and Modified Oligonucleotide Sequences Show Distinct Strand Displacement Kinetics and These Are Affected Further by Molecular Crowders
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DOI: 10.3390/biom12091249
Abstract: DNA and RNA strand exchange is a process of fundamental importance in biology. Herein, we used a FRET-based assay to investigate, for the first time, the stand exchange kinetics of natural DNA, natural RNA, and… read more here.
Keywords: molecular crowders; strand; displacement kinetics; strand displacement ... See more keywords
Investigating Tm Method Specificity Using Oligonucleotide Sequence Variants
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DOI: 10.5731/pdajpst.2021.012694
Abstract: All starting materials and the active pharmaceutical ingredient (API) of a drug product must be subjected to analytical identity (ID) testing as part of the release prior to their introduction into the pharmaceutical manufacturing process.… read more here.
Keywords: method; sequence; investigating method; method specificity ... See more keywords