Oligonucleotide-templated lateral flow assays for amplification-free sensing of circulating microRNAs.
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DOI: 10.1039/c9cc05607f
Abstract: Herein we demonstrate the first example of oligonucleotide-templated reaction (OTR) performed on paper, using lateral flow to capture and concentrate specific nucleic acid biomarkers on a test line. Quantitative analysis, using a low-cost benchtop fluorescence… read more here.
Keywords: flow assays; assays amplification; amplification free; oligonucleotide templated ... See more keywords