Articles with "oligonucleotides robust" as a keyword



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Thiomorpholino oligonucleotides as a robust class of next generation platforms for alternate mRNA splicing

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Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2207956119

Abstract: Significance Splice-switching antisense oligonucleotides (ASOs) represent a unique class of drug molecules with the US Food and Drug Administration approval of Exondys 51, Vyondys 53, Amondys 45, and Viltepso for the treatment of Duchenne muscular… read more here.

Keywords: splice switching; oligonucleotides robust; class; thiomorpholino oligonucleotides ... See more keywords