Thiodipeptides targeting the intestinal oligopeptide transporter as a general approach to improving oral drug delivery
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Medicinal Chemistry"
DOI: 10.1016/j.ejmech.2018.06.064
Abstract: The broad substrate capacity of the intestinal oligopeptide transporter, PepT1, has made it a key target of research into drug delivery. Whilst the substrate capacity of this transporter is broad, studies have largely been limited… read more here.
Keywords: oligopeptide transporter; improving oral; drug delivery; transport ... See more keywords
Chemical Modulation of the Human Oligopeptide Transporter 1, hPepT1.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.7b00775
Abstract: In humans, peptides derived from dietary proteins and peptide-like drugs are transported via the proton-dependent oligopeptide transporter hPepT1 (SLC15A1). hPepT1 is located across the apical membranes of the small intestine and kidney, where it serves… read more here.
Keywords: oligopeptide transporter; hpept1; transporter hpept1; modulation human ... See more keywords
Cloning, phylogenetic analysis, and postnatal expression of oligopeptide transporter PepT1 in gastrointestinal tract of kid goats receiving supplemental feed or pasture
Sign Up to like & getrecommendations! Published in 2020 at "Canadian Journal of Animal Science"
DOI: 10.1139/cjas-2019-0155
Abstract: Abstract: This study aimed to clone the cDNA of PepT1, an H+-dependent oligopeptide transporter, from kid goats and examine effects of physiological development (suckling, weaning, and post-weaning) of the animal and feeding system (supplemental feeding… read more here.
Keywords: oligopeptide transporter; expression; kid goats; phylogenetic analysis ... See more keywords
Analysis of the oligopeptide transporter gene family in Ganoderma lucidum: structure, phylogeny, and expression patterns.
Sign Up to like & getrecommendations! Published in 2017 at "Genome"
DOI: 10.1139/gen-2016-0120
Abstract: Oligopeptide transporters (OPTs) are believed to transport broad ranges of substrates across the plasma membrane from the extracellular environment into the cell and are thought to contribute to various biological processes. In the present study,… read more here.
Keywords: oligopeptide transporter; analysis oligopeptide; analysis; transporter gene ... See more keywords
Genome-Wide Identification and Transcript Analysis Reveal Potential Roles of Oligopeptide Transporter Genes in Iron Deficiency Induced Cadmium Accumulation in Peanut
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.894848
Abstract: The oligopeptide transporter (OPT) family is a group of proton-coupled symporters that play diverse roles, including metal homeostasis. However, little is known about this family of peanuts. To reveal the potential roles of AhOPT genes… read more here.
Keywords: accumulation; oligopeptide transporter; potential roles; deficiency ... See more keywords