Oligoprogression of Solid Tumors on Immune Checkpoint Inhibitors: The Impact of Local Ablative Radiation Therapy
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DOI: 10.3390/biomedicines10102481
Abstract: The breakthrough of a limited number of clones while on immune checkpoint inhibitors (ICIs), known as oligoprogression, has been previously described. The benefit of ablative radiation therapy (RT) directed at these clones, as opposed to… read more here.
Keywords: checkpoint inhibitors; immune checkpoint; ablative radiation; therapy ... See more keywords
The Management of Oligoprogression in the Landscape of New Therapies for Metastatic Melanoma
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DOI: 10.3390/cancers11101559
Abstract: Background: A limited degree of progression after a response to treatment is labelled as oligoprogression and is a hot topic of metastatic melanoma (MM) management. Rogue progressive metastases could benefit from local treatment, which could… read more here.
Keywords: treatment; oligoprogression; management; metastatic melanoma ... See more keywords
Management of Oligoprogression in Patients with Metastatic NSCLC Harboring ALK Rearrangements
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DOI: 10.3390/cancers14030718
Abstract: Simple Summary The growing efficacy and availability of new targeted systemic therapies have markedly improved the prognosis of metastatic lung cancer patients harboring ALK rearrangements. The use of effective targeted therapies capable of maintaining a… read more here.
Keywords: oligoprogression; treatment; disease; alk ... See more keywords
Systemic Therapy for Oligoprogression in Patients with Metastatic NSCLC Harboring Activating EGFR Mutations
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DOI: 10.3390/cancers14030832
Abstract: Simple Summary The oligoprogression concept is characterized by a limited number and/or sites of metastases in which a disease progression appears, and a more indolent tumor biology, raised specifically for oncogene addicted non-small cell lung… read more here.
Keywords: nsclc harboring; egfr mutations; oligoprogression; biology ... See more keywords
Effectiveness of Stereotactic Ablative Radiotherapy for Systemic Therapy Respondents with Inoperable Pulmonary Oligometastases and Oligoprogression
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DOI: 10.3390/diagnostics13091597
Abstract: Stereotactic ablative radiotherapy (SABR) may improve survival in patients with inoperable pulmonary oligometastases. However, the impact of pulmonary oligometastatic status after systemic therapy on SABR outcomes remains unclear. Hence, we investigated the outcomes of SABR… read more here.
Keywords: field; therapy; inoperable pulmonary; pulmonary oligometastases ... See more keywords