Oligosaccharide Chromatographic Techniques for Quantitation of Structural Process-Related Impurities in Heparin Resulting From 2-O Desulfation
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DOI: 10.3389/fmed.2018.00346
Abstract: Heparin is a widely-used intravenous anticoagulant comprising a complex mixture of highly-sulfated linear polysaccharides of repeating sequences of uronic acids (either iduronic or glucuronic) 1->4 linked to D-glucosamine with specific sulfation patterns. Preparation of crude… read more here.
Keywords: heparin; oligosaccharide chromatographic; techniques quantitation; desulfation ... See more keywords