Manganese suppresses the development of oral leukoplakia by activating the immune response.
Sign Up to like & getrecommendations! Published in 2022 at "Oral diseases"
DOI: 10.1111/odi.14412
Abstract: OBJECTIVE Manganese ion (Mn2+ ) is reported to promote the antitumor immune response by activating the cGAS-STING pathway, but it is unknown whether Mn2+ can prevent the malignant transformation of precancerous lesions. The effects of… read more here.
Keywords: mn2; oral leukoplakia; immune response; olk ... See more keywords
Mucoadhesive Nucleoside-Based Hydrogel Delays Oral Leukoplakia Canceration
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Dental Research"
DOI: 10.1177/00220345221085192
Abstract: Some oral squamous cell carcinomas (OSCCs) originate from preexisting oral potentially malignant disorders (OPMDs). Oral leukoplakia (OLK) is the most common and typical OPMD in the clinic, so treatment for it is essential to reduce… read more here.
Keywords: cell; effect; hydrogel; isog ... See more keywords
Multifunctional photodynamic/photothermal nano-agents for the treatment of oral leukoplakia
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Nanobiotechnology"
DOI: 10.1186/s12951-022-01310-2
Abstract: Oral leukoplakia (OLK) has gained extensive attention because of the potential risk for malignant transformation. Photosensitizers (PSs) played an indispensable role in the photodynamic therapy (PDT) of OLK, but the poor light sensitivity greatly hampered… read more here.
Keywords: olk; multifunctional photodynamic; treatment; photodynamic photothermal ... See more keywords
Azoxystrobin induces apoptosis via PI3K/AKT and MAPK signal pathways in oral leukoplakia progression
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.912084
Abstract: Background: Oral leukoplakia (OLK) is one of the oral potentially malignant disorders (OPMDs) with an increased risk of developing oral squamous cell carcinoma (OSCC). There is no ideal therapeutic drug yet. Our previous study showed… read more here.
Keywords: pi3k akt; azox; olk; akt mapk ... See more keywords