Morroniside protects OLN-93 cells against H2O2-induced injury through the PI3K/Akt pathway-mediated antioxidative stress and antiapoptotic activities
Sign Up to like & getrecommendations! Published in 2021 at "Cell Cycle"
DOI: 10.1080/15384101.2021.1889186
Abstract: ABSTRACT Neurodegenerative disorders, including spinal cord injury (SCI), result in oxidative stress-induced cell damage. Morroniside (MR), a major active ingredient of the Chinese herb Shan Zhu Yu, has been shown to ameliorate oxidative stress and… read more here.
Keywords: oln cells; pi3k akt; stress; h2o2 ... See more keywords
The neuroendocrine effects of dehydroepiandrosterone and 17β-estradiol in the in vitro preterm hyperoxia infant model.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of integrative neuroscience"
DOI: 10.31083/j.jin.2021.01.333
Abstract: Preterm birth causes neurological deficits. Previously, we demonstrated that fetal zone steroids reduce hyperoxia-mediated cell death in vitro. In immature oligodendrocytes (OLN-93 cells), dehydroepiandrosterone + 17β-estradiol co-treatment had synergistic beneficial effects while signals were transduced… read more here.
Keywords: estradiol dehydroepiandrosterone; oln cells; hyperoxia; treatment ... See more keywords