Dihydroorotate dehydrogenase inhibitor olorofim has potent in vitro activity against Microascus/Scopulariopsis, Rasamsonia, Penicillium and Talaromyces species
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DOI: 10.1111/myc.13548
Abstract: Treatment options against infections caused by rare but emerging moulds may be limited by their reduced susceptibility or resistance to clinically available antifungals. The investigational antifungal olorofim, which targets the biosynthesis of pyrimidines within fungi,… read more here.
Keywords: dehydrogenase inhibitor; potent vitro; activity; olorofim potent ... See more keywords