Olumacostat glasaretil, a novel topical sebum inhibitor, in the treatment of acne vulgaris: A phase IIa, multicenter, randomized, vehicle‐controlled study
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DOI: 10.1016/j.jaad.2016.08.053
Abstract: Background: Olumacostat glasaretil (OG) inhibits acetyl‐coenzyme A carboxylase, the enzyme responsible for the first, rate‐limiting step in de novo fatty acid synthesis. OG inhibited in vitro human sebocyte lipid production and reduced in vivo sebaceous… read more here.
Keywords: treatment; vehicle; olumacostat glasaretil; acne vulgaris ... See more keywords