Articles with "omalizumab" as a keyword



Anti-IgE treatment in allergic rhinitis.

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Published in 2019 at "International journal of pediatric otorhinolaryngology"

DOI: 10.1016/j.ijporl.2019.109674

Abstract: OBJECTIVES To review the efficacy of anti-IgE therapy in allergic rhinitis (AR). METHODS Literature search was performed using the PubMed and Proquest Central databases at Kırıkkale University Library. RESULTS Although the skin prick testing in… read more here.

Keywords: allergic rhinitis; ige; mast cells; omalizumab ... See more keywords

Development and validation of a new IgE-Tolerant ELISA method for quantifying serum concentration of omalizumab.

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Published in 2020 at "Journal of pharmaceutical and biomedical analysis"

DOI: 10.1016/j.jpba.2020.113120

Abstract: BACKGROUND Omalizumab is effectively used in asthma therapy, but ELISA methods used for omalizumab determination in blood from asthma patients may be interfered by the pre-existing IgE. OBJECTIVE To reduce the effect of pre-existing IgE… read more here.

Keywords: tolerant elisa; omalizumab; ige tolerant; method ... See more keywords

Indirect comparison of bronchial thermoplasty versus omalizumab for uncontrolled severe asthma

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Published in 2018 at "Journal of Asthma"

DOI: 10.1080/02770903.2017.1337789

Abstract: ABSTRACT Objective: Bronchial thermoplasty (BT) as an add-on therapy for uncontrolled severe asthma is an alternative to biologic therapies like omalizumab (OM). We conducted an indirect treatment comparison (ITC) to appraise comparative effectiveness of BT… read more here.

Keywords: omalizumab; treatment; severe asthma; uncontrolled severe ... See more keywords

Association of upper and lower airway eosinophilic inflammation with response to omalizumab in patients with severe asthma

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Published in 2018 at "Journal of Asthma"

DOI: 10.1080/02770903.2018.1541357

Abstract: Abstract Background: The anti-immunoglobulin E monoclonal antibody, omalizumab, is used to treat severe asthma and has the potential to ameliorate airway inflammation. However, the effect of omalizumab in ameliorating upper airway inflammation has not been… read more here.

Keywords: response; omalizumab; severe asthma; inflammation ... See more keywords

Severe non-atopic asthma: omalizumab can reduce severe asthma exacerbations

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Published in 2022 at "Journal of Asthma"

DOI: 10.1080/02770903.2022.2103427

Abstract: Abstract Introduction Humanized monoclonal anti-IgE antibody (omalizumab) has demonstrated efficacy in severe atopic asthma. However, few studies have assessed its efficacy in non-atopic and even less in T2-low severe asthma. The objective was to determinate… read more here.

Keywords: asthma; atopic; non atopic; atopic asthma ... See more keywords

The role of omalizumab in the treatment of chronic rhinosinusitis with nasal polyposis

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Published in 2021 at "Expert Opinion on Biological Therapy"

DOI: 10.1080/14712598.2021.1962282

Abstract: ABSTRACT Introduction: Chronic rhinosinusitis with nasal polyposis (CRSwNP) poses a significant healthcare challenge, with diminished quality of life for patients and high costs and resource utilization for disease management. The understanding of CRSwNP pathophysiology has… read more here.

Keywords: rhinosinusitis nasal; nasal polyposis; omalizumab; treatment ... See more keywords

P23 Successful Control of Systemic Mastocytosis Symptoms in a Two-Year-Old with Omalizumab

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Published in 2024 at "British Journal of Dermatology"

DOI: 10.1093/bjd/ljad483.031

Abstract: A 6-month-old boy presented to us with diffuse cutaneous mastocytosis, experiencing constant severe pruritus, blistering, urticaria, flushing, diarrhoea, and frequent anaphylaxis episodes. He was found to have hepatosplenomegaly and mast cells in the bone marrow… read more here.

Keywords: treatment; p23 successful; systemic mastocytosis; omalizumab ... See more keywords

Successful treatment of urticarial vasculitis with omalizumab in children: a case series.

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Published in 2023 at "Clinical and experimental dermatology"

DOI: 10.1093/ced/llad192

Abstract: Urticarial vasculitis (UV) is a small vessel leukocytoclastic vasculitis, which often needs to be distinguished from urticaria and other dermatoses. Treatment of UV in children is challenging because of the unsatisfying efficacy of antihistamines and… read more here.

Keywords: vasculitis; successful treatment; treatment urticarial; omalizumab ... See more keywords

Efficacy and Safety of Omalizumab for Chronic Spontaneous Urticaria: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

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Published in 2020 at "American Journal of Therapeutics"

DOI: 10.1097/mjt.0000000000000912

Abstract: BACKGROUND Omalizumab has been proposed as a possible effective treatment of chronic spontaneous urticaria (CSU). STUDY QUESTION We aimed to access the efficacy and safety of omalizumab in the treatment of CSU based on qualified,… read more here.

Keywords: safety omalizumab; score; chronic spontaneous; omalizumab ... See more keywords

Model‐based comparisons of post‐treatment free IgE and FEV1 between omalizumab asthma dosing tables in the United States and European Union

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Published in 2024 at "British Journal of Clinical Pharmacology"

DOI: 10.1111/bcp.16197

Abstract: Omalizumab is an anti‐immunoglobulin E (IgE) monoclonal antibody that was first approved by the United States (US) Food and Drug Administration (FDA) for the treatment of allergic asthma in 2003. The pivotal trials supporting the… read more here.

Keywords: united states; asthma dosing; free ige; omalizumab ... See more keywords

Omalizumab may facilitate drug desensitization in patients failing standard protocols

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Published in 2022 at "Pediatric Allergy and Immunology"

DOI: 10.1111/pai.13783

Abstract: subsequent 1 reactions during desensitization trials with rituximab using 12- , 16- and 20- step protocols. desensitization after the first omalizumab dose of 300 mg before 1 week of RDD. 13 Ojaimi et al achieved… read more here.

Keywords: desensitization; may facilitate; omalizumab may; treatment ... See more keywords