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A TRPM7 mutation linked to familial trigeminal neuralgia: Omega current and hyperexcitability of trigeminal ganglion neurons

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Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2119630119

Abstract: Significance This study explores the potential pathogenic effects of a novel mutation of TRPM7 channel (A931T) identified in a 73-year-old man affected by familial trigeminal neuralgia. We show that A931T results in an abnormal Na+… read more here.

Keywords: familial trigeminal; trigeminal neuralgia; omega current; mutation ... See more keywords