Association with polymorphic marmoset cytochrome P450 2C19 of in vivo hepatic clearances of chirally separated R-omeprazole and S-warfarin using individual marmoset physiologically based pharmacokinetic models
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DOI: 10.1080/00498254.2017.1393121
Abstract: Abstract 1. Simulated clearances of R-warfarin and efavirenz were recently reported for individual cynomolgus monkeys genotyped for cytochrome P450 2C19 and 2C9, respectively. To expand and verify this modeling procedure, simulations of R/S-omeprazole and R/S-warfarin… read more here.
Keywords: cytochrome p450; p450 2c19; omeprazole warfarin; using individual ... See more keywords