A multi‐omic approach identifies an autism spectrum disorder (ASD) regulatory complex of functional epimutations in placentas from children born preterm
Sign Up to like & getrecommendations! Published in 2023 at "Autism Research"
DOI: 10.1002/aur.2915
Abstract: Children born preterm are at heightened risk of neurodevelopmental impairments, including Autism Spectrum Disorder (ASD). The placenta is a key regulator of neurodevelopmental processes, though the precise underlying molecular mechanisms remain unclear. Here, we employed… read more here.
Keywords: functional epimutations; multi omic; born preterm; omic approach ... See more keywords
Simultaneous Multiplexed Imaging of Biomolecules in Transgenic Mouse Brain Tissues Using Mass Spectrometry Imaging: A Multi-omic Approach.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c00676
Abstract: The importance of multi-omic-based approaches to better understand diverse pathological mechanisms including neurodegenerative diseases has emerged. Spatial information can be of great help in understanding how biomolecules interact pathologically and in elucidating target biomarkers for… read more here.
Keywords: information; multi omic; mass spectrometry; omic approach ... See more keywords
An omic approach to congenital diaphragmatic hernia: a pilot study of genomic, microRNA, and metabolomic profiling
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Perinatology"
DOI: 10.1038/s41372-020-0623-3
Abstract: Introduction The omic approach can help identify a signature that can be potentially used as biomarkers in babies with congenital diaphragmatic hernia (CDH). Objectives To find a specific microRNA (miR) and metabolic fingerprint of the… read more here.
Keywords: congenital diaphragmatic; omic approach; diaphragmatic hernia; mir mir ... See more keywords