T‐cell responses to SARS‐CoV‐2 Omicron spike epitopes with mutations after the third booster dose of an inactivated vaccine
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27814
Abstract: The rapidly spreading severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) Omicron variant contains more than 30 mutations that mediate escape from antibody responses elicited by prior infection or current vaccines. Fortunately, T‐cell responses are highly… read more here.
Keywords: omicron spike; cell responses; booster; cov omicron ... See more keywords
Do We Really Need Omicron Spike-Based Updated COVID-19 Vaccines? Evidence and Pipeline
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14112488
Abstract: The wild-type SARS-CoV-2 Spike-based vaccines authorized so far have reduced COVID-19 severity, but periodic boosts are required to counteract the decline in immunity. An accelerated rate of immune escape to vaccine-elicited immunity has been associated… read more here.
Keywords: omicron spike; spike based; really need; evidence ... See more keywords
Effects of SARS-CoV-2 Omicron BA.1 Spike Mutations on T-Cell Epitopes in Mice
Sign Up to like & getrecommendations! Published in 2023 at "Viruses"
DOI: 10.3390/v15030763
Abstract: T-cell immunity plays an important role in the control of SARS-CoV-2 and has a great cross-protective effect on the variants. The Omicron BA.1 variant contains more than 30 mutations in the spike and severely evades… read more here.
Keywords: omicron spike; spike mutations; cell epitopes; sars cov ... See more keywords