Comprehensive omics studies of p53 mutants in human cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in functional genomics"
DOI: 10.1093/bfgp/elac015
Abstract: The p53 is the master regulator of the cell known for regulating a large array of cellular processes. Inactivation of p53 by missense mutations is one of the leading causes of cancer. Some of these… read more here.
Keywords: studies p53; omics studies; p53 mutants; p53 ... See more keywords
From single- to multi-omics: future research trends in medicinal plants
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbac485
Abstract: Abstract Medicinal plants are the main source of natural metabolites with specialised pharmacological activities and have been widely examined by plant researchers. Numerous omics studies of medicinal plants have been performed to identify molecular markers… read more here.
Keywords: multi omics; omics studies; single multi; studies medicinal ... See more keywords
Non-coding RNAs and Alzheimer's disease: perspectives from omics studies.
Sign Up to like & getrecommendations! Published in 2022 at "Human molecular genetics"
DOI: 10.1093/hmg/ddac202
Abstract: Neurodegenerative diseases such as Alzheimer's disease (AD) are characterized by the progressive loss of neurons in the brain and the spinal cord. The pathophysiology of AD is multifactorial with heterogeneous molecular manifestations. The lack of… read more here.
Keywords: omics studies; coding rnas; disease; alzheimer disease ... See more keywords
What did we learn from ‘omics’ studies in osteoarthritis
Sign Up to like & getrecommendations! Published in 2018 at "Current Opinion in Rheumatology"
DOI: 10.1097/bor.0000000000000460
Abstract: Purpose of review ‘Omics’ technologies developed for the massive analysis of the major biologically relevant molecules (genes, proteins, metabolites) have been applied to the study of osteoarthritis (OA) for more than a decade. Recent findings… read more here.
Keywords: omics studies; rheumatology; learn omics; studies osteoarthritis ... See more keywords
Omics studies in gastroenterological and hepatological patient populations: current impact and future promise exemplified by a large study of HCV-infected livers
Sign Up to like & getrecommendations! Published in 2022 at "Gut"
DOI: 10.1136/gutjnl-2022-327761
Abstract: ‘But, where’s the beef?’, a colleague and friend asked me at a conference, right after a student from my group had presented our first transcriptional data set on T cells in viral hepatitis. I knew… read more here.
Keywords: liver; omics studies; expression; analysis ... See more keywords
Delineating the molecular responses of a halotolerant microalga using integrated omics approach to identify genetic engineering targets for enhanced TAG production
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology for Biofuels"
DOI: 10.1186/s13068-018-1343-1
Abstract: BackgroundHarnessing the halotolerant characteristics of microalgae provides a viable alternative for sustainable biomass and triacylglyceride (TAG) production. Scenedesmus sp. IITRIND2 is a fast growing fresh water microalga that has the capability to thrive in high… read more here.
Keywords: delineating molecular; halotolerant microalga; production; omics studies ... See more keywords
Deciphering the Complex Molecular Pathogenesis of Myotonic Dystrophy Type 1 through Omics Studies
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23031441
Abstract: Omics studies are crucial to improve our understanding of myotonic dystrophy type 1 (DM1), the most common muscular dystrophy in adults. Employing tissue samples and cell lines derived from patients and animal models, omics approaches… read more here.
Keywords: omics studies; dystrophy type; dystrophy; myotonic dystrophy ... See more keywords
What Has Longitudinal ‘Omics’ Studies Taught Us about Irritable Bowel Syndrome? A Systematic Review
Sign Up to like & getrecommendations! Published in 2023 at "Metabolites"
DOI: 10.3390/metabo13040484
Abstract: Irritable bowel syndrome is a prototypical disorder of the brain–gut–microbiome axis, although the underlying pathogenesis and mechanisms remain incompletely understood. With the recent advances in ‘omics’ technologies, studies have attempted to uncover IBS-specific variations in… read more here.
Keywords: omics studies; studies taught; irritable bowel; longitudinal omics ... See more keywords