Engineered Bacterial Outer Membrane Vesicles as Controllable Two‐Way Adaptors to Activate Macrophage Phagocytosis for Improved Tumor Immunotherapy
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DOI: 10.1002/adma.202206200
Abstract: The most immune cells infiltrating tumor microenvironment (TME), tumor‐associated macrophages (TAMs) closely resemble immunosuppressive M2‐polarized macrophages. Moreover, tumor cells exhibit high expression of CD47 “don't eat me” signal, which obstructs macrophage phagocytosis. The precise and… read more here.
Keywords: two way; phagocytosis; cd47nb; omv cd47nb ... See more keywords