Onchocerciasis (River Blindness) - more than a Century of Research and Control.
Sign Up to like & getrecommendations! Published in 2020 at "Acta tropica"
DOI: 10.1016/j.actatropica.2020.105677
Abstract: This review summarises more than a century of research on onchocerciasis, also known as river blindness, and its control. River blindness is an infection caused by the tissue filaria Onchocerca volvulus affecting the skin, subcutaneous… read more here.
Keywords: control; river blindness; onchocerciasis; century research ... See more keywords
High prevalence of epilepsy in an onchocerciasis endemic health zone in the Democratic Republic of the Congo, despite 14 years of community-directed treatment with ivermectin: A mixed-method assessment
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Infectious Diseases"
DOI: 10.1016/j.ijid.2018.10.021
Abstract: Highlights • A high epilepsy prevalence in the Aketi health zone was observed despite 14 years of community-directed treatment with ivermectin.• The high prevalence of OV16 antibodies in children is indicative of high ongoing onchocerciasis… read more here.
Keywords: despite years; community directed; prevalence; years community ... See more keywords
The Current Status of Molecular Xenomonitoring for Lymphatic Filariasis and Onchocerciasis.
Sign Up to like & getrecommendations! Published in 2017 at "Trends in parasitology"
DOI: 10.1016/j.pt.2017.06.008
Abstract: The capacity of vector insect surveillance to provide estimates of pathogen prevalence and transmission potential has long been recognized within the global communities tasked with eliminating lymphatic filariasis (LF), the underlying cause of elephantiasis and… read more here.
Keywords: status molecular; lymphatic filariasis; molecular xenomonitoring; current status ... See more keywords
Sara Lustigman: Developing a vaccine to accelerate onchocerciasis elimination.
Sign Up to like & getrecommendations! Published in 2018 at "Trends in parasitology"
DOI: 10.1016/j.pt.2017.11.001
Abstract: Sara Lustigman leads the Laboratory of Molecular Parasitology at the Lindsley F. Kimball Research Institute of the New York Blood Center. Sara and her team are currently focused on developing a prophylactic vaccine for onchocerciasis,… read more here.
Keywords: parasitology; diff; onchocerciasis; biology ... See more keywords
Onchocerciasis-Associated Epilepsy, an Additional Reason for Strengthening Onchocerciasis Elimination Programs.
Sign Up to like & getrecommendations! Published in 2018 at "Trends in parasitology"
DOI: 10.1016/j.pt.2017.11.009
Abstract: A high prevalence of epilepsy has been observed in onchocerciasis-endemic regions with high onchocerciasis transmission. Recent epidemiological studies suggest that Onchocerca volvulus infection is the trigger causing the seizures, which appear in previously healthy children… read more here.
Keywords: reason strengthening; onchocerciasis associated; additional reason; strengthening onchocerciasis ... See more keywords
Development of a recombinant vaccine against human onchocerciasis.
Sign Up to like & getrecommendations! Published in 2021 at "Expert review of vaccines"
DOI: 10.1080/14760584.2021.1977125
Abstract: IntroductionHuman onchocerciasis caused by the filarial nematode parasite Onchocerca volvulus remains a major cause of debilitating disease infecting millions primarily in Sub-Saharan Africa. The development of a prophylactic vaccine, along with mass drug administration, would… read more here.
Keywords: vaccine; development recombinant; protective immunity; onchocerciasis ... See more keywords
The interruption of transmission of onchocerciasis in Kaduna, Kebbi and Zamfara states, Nigeria: another milestone achievement
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DOI: 10.1093/inthealth/ihac036
Abstract: Abstract Background More than 40 million people live in onchocerciasis-endemic areas in Nigeria. For at least 19 y, mass drug administration (MDA) with ivermectin was implemented with at least 65% total population coverage in Kaduna,… read more here.
Keywords: zamfara states; kebbi zamfara; transmission; onchocerciasis ... See more keywords
Cross-border issues: an important component of onchocerciasis elimination programmes.
Sign Up to like & getrecommendations! Published in 2018 at "International health"
DOI: 10.1093/inthealth/ihx058
Abstract: Endemic areas that involve national or local borders present an important challenge to the success of elimination of onchocerciasis; such cross-border endemic foci require special attention to ensure that programme activities are unified. It is… read more here.
Keywords: cross border; onchocerciasis; border issues; elimination ... See more keywords
Imported onchocerciasis in migrants and travelers
Sign Up to like & getrecommendations! Published in 2018 at "Current Opinion in Infectious Diseases"
DOI: 10.1097/qco.0000000000000483
Abstract: Purpose of review With increasing international travel and mass global population migration, clinicians in nonendemic countries must be familiar with imported neglected tropical diseases including onchocerciasis, which is commonly known as ‘river blindness’. Recent findings… read more here.
Keywords: imported onchocerciasis; onchocerciasis migrants; migrants travelers; onchocerciasis ... See more keywords
An appraisal of the neglected tropical diseases control program in Cameroon: the case of the national program against onchocerciasis
Sign Up to like & getrecommendations! Published in 2017 at "BMC Public Health"
DOI: 10.1186/s12889-017-4037-x
Abstract: BackgroundOnchocerciasis is a severe parasitic infestation which causes disabling skin and subcutaneous tissue changes. Current global estimates suggest that it accounts for 1135.7 disability adjusted life years (DALYs) per 100,000 population. The disease is endemic… read more here.
Keywords: control program; program cameroon; disease; cameroon ... See more keywords
The role of 'omics' in the quest to eliminate human filariasis
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0005464
Abstract: Lymphatic filariasis (LF) is a disease affecting approximately 120 million people in over 73 countries [1] and caused by infection with a group of filarial nematodes transmitted by mosquito vectors. Wuchereria bancrofti is responsible for… read more here.
Keywords: filariasis; mda; lymphatic filariasis; control ... See more keywords