Abstract 872: Genetic models reveal that the novelVGLL2-NCOA2fusion oncogene leverages embryonic programs for sarcomagenesis
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DOI: 10.1158/1538-7445.sabcs18-872
Abstract: Rhabdomyosarcoma (RMS) is an aggressive pediatric cancer characterized by a misregulation of skeletal muscle developmental pathways. To date, identified oncogenic drivers predominantly include RAS mutations or chromosomal translocations and gene fusions between PAX3 or PAX7… read more here.
Keywords: vgll2 ncoa2; models reveal; vgll2; leverages embryonic ... See more keywords