Human endogenous retroviruses in cancer: Oncogenesis mechanisms and clinical implications
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28350
Abstract: Human Endogenous Retroviruses (HERVs) are viral sequences integrated into the human genome, resulting from the infection of human germ‐line cells by ancient exogenous retroviruses. Despite losing their replication and retrotransposition abilities, HERVs appear to have… read more here.
Keywords: oncogenesis mechanisms; human endogenous; retroviruses cancer; cancer oncogenesis ... See more keywords
Interplay between epigenetics and metabolism in oncogenesis: mechanisms and therapeutic approaches
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DOI: 10.1038/onc.2016.485
Abstract: Epigenetic and metabolic alterations in cancer cells are highly intertwined. Oncogene-driven metabolic rewiring modifies the epigenetic landscape via modulating the activities of DNA and histone modification enzymes at the metabolite level. Conversely, epigenetic mechanisms regulate… read more here.
Keywords: epigenetics metabolism; oncogenesis mechanisms; mechanisms therapeutic; metabolism ... See more keywords