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Published in 2018 at "Journal of Thoracic Oncology"
DOI: 10.1016/j.jtho.2018.07.061
Abstract: Background: Profiling of targetable oncogenic drivers has significantly improved outcomes in patients with nonesmall cell lung cancer (NSCLC). About 40% of individuals with metastatic lung adenocarcinomas may benefit from personalized treatment with kinase inhibitors. There…
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Keywords:
patients included;
oncogenic drivers;
rwt osimertinib;
astris rwt ... See more keywords
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Published in 2018 at "Nature genetics"
DOI: 10.1038/s41588-018-0078-z
Abstract: Comprehensive genomic characterization of prostate cancer has identified recurrent alterations in genes involved in androgen signaling, DNA repair, and PI3K signaling, among others. However, larger and uniform genomic analysis may identify additional recurrently mutated genes…
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Keywords:
tail oncogenic;
long tail;
oncogenic drivers;
prostate cancer ... See more keywords
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Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.665484
Abstract: Background Several oncogenic drivers in non-small cell lung cancer (NSCLC) are considered actionable with available or promising targeted therapies. Although targetable drivers rarely overlap with each other, there were a minority of patients harboring co-occurring…
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Keywords:
drivers non;
actionable oncogenic;
oncogenic drivers;
occurring potentially ... See more keywords