Articles with "oncogenic drivers" as a keyword



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ASTRIS a RWT with Osimertinib in NSCLC EGFR T790M Mutated: Disease Characteristics from Patients Included in Argentina: P22

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Published in 2018 at "Journal of Thoracic Oncology"

DOI: 10.1016/j.jtho.2018.07.061

Abstract: Background: Profiling of targetable oncogenic drivers has significantly improved outcomes in patients with nonesmall cell lung cancer (NSCLC). About 40% of individuals with metastatic lung adenocarcinomas may benefit from personalized treatment with kinase inhibitors. There… read more here.

Keywords: patients included; oncogenic drivers; rwt osimertinib; astris rwt ... See more keywords
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The long tail of oncogenic drivers in prostate cancer

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Published in 2018 at "Nature genetics"

DOI: 10.1038/s41588-018-0078-z

Abstract: Comprehensive genomic characterization of prostate cancer has identified recurrent alterations in genes involved in androgen signaling, DNA repair, and PI3K signaling, among others. However, larger and uniform genomic analysis may identify additional recurrently mutated genes… read more here.

Keywords: tail oncogenic; long tail; oncogenic drivers; prostate cancer ... See more keywords
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Co-Occurring Potentially Actionable Oncogenic Drivers in Non-Small Cell Lung Cancer

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Published in 2021 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2021.665484

Abstract: Background Several oncogenic drivers in non-small cell lung cancer (NSCLC) are considered actionable with available or promising targeted therapies. Although targetable drivers rarely overlap with each other, there were a minority of patients harboring co-occurring… read more here.

Keywords: drivers non; actionable oncogenic; oncogenic drivers; occurring potentially ... See more keywords