Immune checkpoints in T cells during oncogenic γ‐herpesvirus infections
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27840
Abstract: Epstein–Barr virus (EBV) and Kaposi sarcoma‐associated herpesvirus (KSHV) are two persistent oncogenic γ‐herpesviruses with an exclusive tropism for humans. They cause cancers of lymphocyte, epithelial and endothelial cell origin, such as Burkitt's and Hodgkin's lymphoma,… read more here.
Keywords: checkpoints cells; immune checkpoints; ebv kshv; cells oncogenic ... See more keywords
Modeling oncogenic herpesvirus infections in humanized mice.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in virology"
DOI: 10.1016/j.coviro.2020.07.005
Abstract: The creation of humanized mice generally involves the reconstitution of immunodeficient mice with human immune constituents. Different methodologies have been employed, and significant progress has been made towards the development of robustly humanized mouse models.… read more here.
Keywords: virology; oncogenic herpesvirus; herpesvirus infections; humanized mice ... See more keywords
DEAD/DEAH-box helicase 5 is hijacked by an avian oncogenic herpesvirus to inhibit interferon beta production and promote viral replication.
Sign Up to like & getrecommendations! Published in 2021 at "Developmental and comparative immunology"
DOI: 10.1016/j.dci.2021.104048
Abstract: DEAD-box helicase 5 (DDX5) plays a significant role in tumorigenesis and regulates viral replication of several viruses. An avian oncogenic herpesvirus, Marek's disease virus (MDV), is widely known to cause immunosuppression and lymphoma in chickens.… read more here.
Keywords: viral replication; production; oncogenic herpesvirus; avian oncogenic ... See more keywords
Berberine in Human Oncogenic Herpesvirus Infections and Their Linked Cancers
Sign Up to like & getrecommendations! Published in 2021 at "Viruses"
DOI: 10.3390/v13061014
Abstract: Human herpesviruses are known to induce a broad spectrum of diseases, ranging from common cold sores to cancer, and infections with some types of these viruses, known as human oncogenic herpesviruses (HOHVs), can cause cancer.… read more here.
Keywords: berberine human; oncogenic herpesvirus; infections linked; herpesvirus infections ... See more keywords