Correspondence: Reply to ‘Oncogenic MYC persistently upregulates the molecular clock component REV-ERBα'
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms14918
Abstract: Correspondence: Reply to ‘Oncogenic MYC persistently upregulates the molecular clock component REV-ERBα’ read more here.
Keywords: correspondence reply; reply oncogenic; persistently upregulates; upregulates molecular ... See more keywords
Runx3 is required for oncogenic Myc upregulation in p53-deficient osteosarcoma
Sign Up to like & getrecommendations! Published in 2021 at "Oncogene"
DOI: 10.1038/s41388-021-02120-w
Abstract: Osteosarcoma (OS) in human patients is characterized by genetic alteration of TP53. Osteoprogenitor-specific p53-deleted mice (OS mice) have been widely used to study the process of osteosarcomagenesis. However, the molecular mechanisms responsible for the development… read more here.
Keywords: p53 deficient; p53; oncogenic myc; runx3 ... See more keywords
S146L in MYC is a context-dependent activating substitution in cancer development
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0272771
Abstract: MYC is one of the most dysregulated oncogenes and is thought to be fundamental to tumor formation and/or maintenance in many cancer types. This dominant pro-tumor activity makes MYC an attractive target for cancer therapy.… read more here.
Keywords: substitution; oncogenic myc; myc; activity ... See more keywords