Tcf1 is essential for initiation of oncogenic Notch1-driven chromatin topology in T-ALL
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DOI: 10.1182/blood.2021012077
Abstract: Abstract NOTCH1 is a well-established lineage specifier for T cells and among the most frequently mutated genes throughout all subclasses of T cell acute lymphoblastic leukemia (T-ALL). How oncogenic NOTCH1 signaling launches a leukemia-prone chromatin… read more here.
Keywords: topology; oncogenic notch1; tcf1; tcf1 essential ... See more keywords