Articles with "oncogenic potential" as a keyword



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RNA-seq Based Transcription Characterization of Fusion Breakpoints as a Potential Estimator for Its Oncogenic Potential

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Published in 2017 at "BioMed Research International"

DOI: 10.1155/2017/9829175

Abstract: Based on high-throughput sequencing technology, the detection of gene fusions is no longer a big challenge but estimating the oncogenic potential of fusion genes remains challenging. Recent studies successfully applied machine learning methods and gene… read more here.

Keywords: oncogenic potential; fusion clone; fusion mutation; fusion ... See more keywords
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The Transcriptional Regulator Sin3A Contributes to the Oncogenic Potential of STAT3.

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Published in 2019 at "Cancer research"

DOI: 10.1158/0008-5472.can-18-0359

Abstract: Epigenetic silencing of promoter and enhancer regions is a common phenomenon in malignant cells. The transcription factor STAT3 is aberrantly activated in several tumors, where its constitutive acetylation accounts for the transcriptional repression of a… read more here.

Keywords: stat3; stat3 acetylation; sin3a; cell ... See more keywords
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Oncogenic Potential of the Dual-Function Protein MEX3A

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Published in 2021 at "Biology"

DOI: 10.3390/biology10050415

Abstract: Simple Summary RNA-binding proteins (RBPs) are involved in the post-transcriptional control of gene expression, modulating the splicing, turnover, subcellular sorting and translation of (m)RNAs. Dysregulation of RBPs, for instance, by deregulated expression in cancer, disturbs… read more here.

Keywords: protein; oncogenic potential; rna binding; expression ... See more keywords
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Regulator of G Protein Signaling 20 Correlates with Long Intergenic Non-Coding RNA (lincRNAs) Harboring Oncogenic Potential and Is Markedly Upregulated in Hepatocellular Carcinoma

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Published in 2022 at "Biology"

DOI: 10.3390/biology11081174

Abstract: Simple Summary Clinical and molecular advances have improved knowledge and treatment prospects for cancer, yet hepatocellular carcinoma (HCC), the most common form of liver cancer, still ranks significantly higher in terms of the global cancer… read more here.

Keywords: oncogenic potential; hepatocellular carcinoma; hcc; protein signaling ... See more keywords