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Published in 2021 at "Human Genetics"
DOI: 10.1007/s00439-021-02396-8
Abstract: Long non-coding RNAs (lncRNAs) have been gaining importance in the field of cancer research in recent years. PRNCR1 (prostate cancer-associated non-coding RNA1) is a 12.7 kb, intron-less lncRNA found to play an oncogenic role in…
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Keywords:
prncr1;
oncogenic role;
long non;
non coding ... See more keywords
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Published in 2017 at "Cancer letters"
DOI: 10.1016/j.canlet.2017.08.024
Abstract: Medulloblastoma is the most common solid tumor among children. Current therapeutic strategies for this malignancy include surgical resection, radiation therapy and chemotherapy. However, these treatments are accompanied with serious side effects such as neurological complications…
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Keywords:
oncogenic role;
role cytomegalovirus;
cytomegalovirus medulloblastoma;
cytomegalovirus ... See more keywords
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Published in 2017 at "Cancer cell"
DOI: 10.1016/j.ccell.2016.11.017
Abstract: N6-Methyladenosine (m6A) represents the most prevalent internal modification in mammalian mRNAs. Despite its functional importance in various fundamental bioprocesses, the studies of m6A in cancer have been limited. Here we show that FTO, as an…
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Keywords:
role acute;
m6a;
oncogenic role;
myeloid leukemia ... See more keywords
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Published in 2021 at "Journal of Oncology"
DOI: 10.1155/2021/2986444
Abstract: Chromatin-modifying enzymes, especially protein arginine methyltransferases (PRMTs), have been identified as candidate targets for cancer. Cellular or animal-based evidence has suggested an association between coactivator-linked arginine methyltransferase 1 (CARM1) and cancer progression. However, the relationship…
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Keywords:
oncogenic role;
infiltration;
carm1;
immune infiltration ... See more keywords
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Published in 2017 at "Cancer research"
DOI: 10.1158/0008-5472.can-17-0298
Abstract: SND1, a subunit of the miRNA regulatory complex RISC, has been implicated as an oncogene in hepatocellular carcinoma (HCC). In this study, we show that hepatocyte-specific SND1 transgenic mice (Alb/SND1 mice) develop spontaneous HCC with…
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Keywords:
hepatocellular carcinoma;
role snd1;
oncogenic role;
mice ... See more keywords
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Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-3386
Abstract: Liver cancer (hepatocellular carcinoma, HCC) is one of the most prevalent malignancies worldwide. Because of the late diagnosis of the disease, the prognosis of HCC patient is often undesirable. Cancer Stem Cell (CSC), which represents…
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Keywords:
hepatocellular carcinoma;
oncogenic role;
cd133;
role cd133 ... See more keywords
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Published in 2022 at "Cancer Cell International"
DOI: 10.1186/s12935-022-02525-x
Abstract: Background Programmed Cell Death 2 Like (PDCD2L) correlates with cell proliferation, apoptosis and mouse embryonic development. However, the role of PDCD2L in human cancers is unclear. Methods Multiple bioinformatic methods, in vitro function experiments and…
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Keywords:
cancer;
pdcd2l;
carcinoma;
cell ... See more keywords
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Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.994440
Abstract: Purpose: The purpose of this study was to explore the oncogenic role of small nuclear ribonucleoprotein polypeptides B and B1 (SNRPB) in human tumors. Materials and methods: Study cases were acquired from The Cancer Genome…
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Keywords:
role;
human tumors;
snrpb human;
expression ... See more keywords
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Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23020930
Abstract: Circular RNAs (circRNAs) and long noncoding RNAs (lncRNAs) are differentially expressed in gastrointestinal cancers. These noncoding RNAs (ncRNAs) regulate a variety of cellular activities by physically interacting with microRNAs and proteins and altering their activity.…
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Keywords:
circrnas lncrnas;
gastrointestinal cancers;
role exosomal;
long noncoding ... See more keywords