DNMT1 as a therapeutic target in pancreatic cancer: mechanisms and clinical implications
Sign Up to like & getrecommendations! Published in 2020 at "Cellular Oncology"
DOI: 10.1007/s13402-020-00526-4
Abstract: Background Pancreatic cancer or pancreatic ductal adenocarcinoma (PDAC) is one of the most devastating cancer types with a 5-year survival rate of only 9%. PDAC is one of the leading causes of cancer-related deaths in… read more here.
Keywords: pdac; tumor suppressor; oncogenic roles; pancreatic cancer ... See more keywords
The genetic alteration spectrum of the SWI/SNF complex: The oncogenic roles of BRD9 and ACTL6A
Sign Up to like & getrecommendations! Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0222305
Abstract: SWItch/Sucrose NonFermentable (SWI/SNF) is a set of multi-subunits chromatin remodeling complexes, playing important roles in a variety of biological processes. Loss-of-function mutations in the genes encoding SWI/SNF subunits have been reported in more than 20%… read more here.
Keywords: oncogenic roles; spectrum swi; genetic alteration; alteration spectrum ... See more keywords
Oncogenic Roles of Small Nucleolar RNA Host Gene 7 (SNHG7) Long Noncoding RNA in Human Cancers and Potentials
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.809345
Abstract: Long noncoding RNAs (lncRNAs) are a class of noncoding transcripts characterized with more than 200 nucleotides of length. Unlike their names, some short open reading frames are recognized for them encoding small proteins. LncRNAs are… read more here.
Keywords: rna; long noncoding; human cancers; oncogenic roles ... See more keywords
The Oncogenic Roles of JC Virus T Antigen in Breast Carcinogenesis
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2021.687444
Abstract: Purpose: JC virus (JCV) infects 80–90% of the population and results in progressive multifocal leukoencephalopathy upon immunodeficiency. The study aimed to pathologically clarify the oncogenic roles of T antigen in human breast cancers. Methods: Breast… read more here.
Keywords: breast; oncogenic roles; breast cancer; jcv ... See more keywords
The oncogenic roles of JC polyomavirus in cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.976577
Abstract: JC polyomavirus (JCPyV) belongs to the human polyomavirus family. Based on alternative splicing, the early region encodes the large and small T antigens, while the late region encodes the capsid structural proteins (VP1, VP2, and… read more here.
Keywords: dna; jcpyv; oncogenic roles; polyomavirus cancer ... See more keywords
Exploring the oncogenic roles of LINC00857 in pan-cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.996686
Abstract: Although aberrant LINC00857 expression may play a key role in oncogenesis, no research has analyzed the pan-cancer oncogenic roles of LINC00857, particularly in tumor immunology. Here, we integrated data from several databases to analyze the… read more here.
Keywords: pan cancer; expression; linc00857 pan; roles linc00857 ... See more keywords
Tumor-Suppressive and Oncogenic Roles of microRNA-149-5p in Human Cancers
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231810823
Abstract: Malignant tumors are always a critical threat to human health, with complex pathogenesis, numerous causative factors, and poor prognosis. The features of cancers, such as gene mutations, epigenetic alterations, and the activation and inhibition of… read more here.
Keywords: tumor suppressive; mir 149; roles microrna; human cancers ... See more keywords