Hallmarks and Determinants of Oncogenic Translation Revealed by Ribosome Profiling in Models of Breast Cancer☆
Sign Up to like & getrecommendations! Published in 2020 at "Translational Oncology"
DOI: 10.1016/j.tranon.2019.12.002
Abstract: Gene expression is extensively and dynamically modulated at the level of translation. How cancer cells prioritize the translation of certain mRNAs over others from a pool of competing mRNAs remains an open question. Here, we… read more here.
Keywords: ribosome profiling; oncogenic translation; breast cancer; models breast ... See more keywords
Abstract IA06: Oncogenic translation programs
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.transcontrol16-ia06
Abstract: New York, NY. I will provide an overview of the lab9s contribution to deciphering the role of aberrant mRNA translation in cancer. We initially reported that aberrant eIF4E expression can drive lymphomagenesis in vivo. Next,… read more here.
Keywords: translation programs; abstract ia06; oncogenic translation; translation ... See more keywords