Bayesian two-stage design for phase II oncology trials with binary endpoint.
Sign Up to like & getrecommendations! Published in 2022 at "Statistics in medicine"
DOI: 10.1002/sim.9355
Abstract: In phase II oncology trials, two-stage design allowing early stopping for futility and/or efficacy is frequently used. However, this design based on frequentist statistical approaches could not guarantee a high posterior probability of attending the… read more here.
Keywords: oncology trials; two stage; phase oncology; oncology ... See more keywords
Sponsorship of pediatric oncology interventional trials.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.10044
Abstract: 10044 Background: The sponsor of a clinical trial is the single entity responsible for the overall conduct and oversight of the trial. Sponsors may be pharmaceutical/biotech companies (“industry”), government agencies (e.g. NIH), or other entities… read more here.
Keywords: interventional trials; industry government; oncology; industry ... See more keywords