Oncolytic Activity of the Vaccine Strain of Type 3 Poliovirus on the Model of Rat Glioma C6 Cells
Sign Up to like & getrecommendations! Published in 2019 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-019-04472-6
Abstract: Rat glioma cell line C6 expressing human poliovirus receptor (PVR) and susceptible to polioviruses (C6-PVR-BFP) was used to produce a clone with knockout of IFNα/β (Ifnar1) receptor subunit 1 gene (Ifnar1). The sensitivity of C6-PVR-BFP… read more here.
Keywords: rat glioma; vaccine strain; oncolytic activity; type ... See more keywords
Immunostimulatory oncolytic activity of coxsackievirus A11 in human malignant pleural mesothelioma
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DOI: 10.1111/cas.15645
Abstract: Malignant pleural mesothelioma (MPM) is an aggressive solid cancer with a poor prognosis, whereas coxsackievirus A11 (CVA11) is a potential oncolytic virus for cancer treatment. We here investigated the oncolytic activity of CVA11 with human… read more here.
Keywords: malignant pleural; oncolytic activity; pleural mesothelioma; cva11 ... See more keywords
Novel group C oncolytic adenoviruses carrying a microRNA inhibitor demonstrate enhanced oncolytic activity in vitro and in vivo.
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DOI: 10.1158/1535-7163.mct-21-0240
Abstract: Oncolytic adenoviruses (OAds) represent an attractive treatment option for cancer. Clinical efficacy of commonly utilized human Ad type 5 (Ad5) based oncolytic viruses is limited by variable expression levels of the coxsackie- and adenovirus receptor… read more here.
Keywords: oncolytic adenoviruses; enhanced oncolytic; oncolytic activity; tumor ... See more keywords
SARS-CoV-2 RBD protein enhances the oncolytic activity of the vesicular stomatitis virus
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DOI: 10.3389/fimmu.2023.1082191
Abstract: Despite recent advances in the research on oncolytic viruses (OVs), a better understanding of how to enhance their replication is key to improving their therapeutic index. Understanding viral replication is important to improve treatment outcomes… read more here.
Keywords: vsv; oncolytic activity; cov rbd; virus ... See more keywords