STING and IRF3 in stromal fibroblasts enable sensing of genomic stress in cancer cells to undermine oncolytic viral therapy
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DOI: 10.1038/s41556-020-0527-7
Abstract: Cancer-associated fibroblasts (CAFs) perform diverse roles and can modulate therapy responses 1 . The inflammatory environment within tumours also influences responses to many therapies, including the efficacy of oncolytic viruses 2 ; however, the role… read more here.
Keywords: therapy; sting irf3; oncolytic viral; cancer cells ... See more keywords