How Does the Recently Discovered Peptide MIP Exhibit Much Higher Binding Affinity than an Anticancer Protein p53 for an Oncoprotein MDM2?
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DOI: 10.1021/acs.jcim.9b00226
Abstract: An oncoprotein MDM2 binds to the extreme N-terminal peptide region of a tumor suppressor protein p53 (p53NTD) and inhibits its anticancer activity. We recently discovered a peptide named MIP which exhibits much higher binding affinity… read more here.
Keywords: affinity; mdm2; oncoprotein mdm2; recently discovered ... See more keywords