Deletion of Regulatory Elements with All-in-One CRISPR-Cas9 Vectors.
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DOI: 10.1007/978-1-0716-1597-3_18
Abstract: Loss-of-function experiments are essential for the functional investigation of cis-regulatory elements (CREs), such as transcriptional enhancers. This can be achieved with CRISPR-Cas9 using pairs of single guide RNAs (sgRNAs) to target the flanking regions of… read more here.
Keywords: crispr cas9; deletion regulatory; one crispr; regulatory elements ... See more keywords