Design, synthesis, and antidepressant/anticonvulsant activities of 3H-benzo[f]chromen chalcone derivatives
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DOI: 10.1007/s00044-021-02742-5
Abstract: In this study, 19 3H-benzo[f]chromen chalcone derivatives (2a–2s) were obtained from 2-hydroxy-1-naphthaldehyde as the starting material, and their structures were confirmed by IR, 1H NMR, 13C NMR, and ESI-MS analyses. The antidepressant activities of the… read more here.
Keywords: chromen chalcone; design synthesis; activity; benzo chromen ... See more keywords
572. Real-world Effectiveness of COVID-19 mRNA Vaccines against Hospitalizations and Deaths in a Retrospective Cohort
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DOI: 10.1093/ofid/ofab466.770
Abstract: Abstract Background The effectiveness of Severe Acute Respiratory Syndrome Coronavirus 2 vaccines after two doses needs to be demonstrated beyond clinical trials. Methods In a retrospective cohort assembled from a cross-institution comprehensive data repository, established… read more here.
Keywords: one dose; two doses; effectiveness; covid ... See more keywords
One versus two doses of ivermectin-based mass drug administration for the control of scabies: A cluster randomised non-inferiority trial
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DOI: 10.1371/journal.pntd.0011207
Abstract: Background Mass drug administration (MDA) based on two doses of ivermectin, one week apart, substantially reduces prevalence of both scabies and impetigo. The Regimens of Ivermectin for Scabies Elimination (RISE) trial assessed whether one-dose ivermectin-based… read more here.
Keywords: ivermectin based; one dose; dose; scabies prevalence ... See more keywords