Articles with "one mannich" as a keyword



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2-(3-Hydroxybenzyl)benzo[d]isothiazol-3(2H)-one Mannich base derivatives as potential multifunctional anti-Alzheimer’s agents

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Published in 2021 at "Medicinal Chemistry Research"

DOI: 10.1007/s00044-021-02725-6

Abstract: A series of 2-(3-hydroxybenzyl)benzo[d]isothiazol-3(2H)-one Mannich base derivatives were designed as potential multifunctional agents against Alzheimer’s disease. The twelve derivatives were synthesized and evaluated with various biological activities. In vitro, biological assays showed that most of… read more here.

Keywords: benzo isothiazol; mannich base; base derivatives; hydroxybenzyl benzo ... See more keywords