Limiting Transactivator Amounts Contribute to Transgene Mosaicism in Tet-On All-in-One Systems.
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DOI: 10.1021/acssynbio.2c00036
Abstract: MicroRNAs play an essential role in cell homeostasis and have been proposed as therapeutic agents. One strategy to deliver microRNAs is to genetically engineer target cells to express microRNAs of interest. However, to control dosage… read more here.
Keywords: tet one; transactivator; expression; tet ... See more keywords