Assembly of Benzo[c][1,2]dithiol-3-ones via Acid-Promoted Denitrogenative Transannulation of Benzotriazinones.
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DOI: 10.1021/acs.orglett.2c03638
Abstract: An expedient synthesis of benzo[c][1,2]dithiol-3-ones via metal-free denitrogenative transannulation of benzotriazinones is developed, which represents the first example of acid-mediated heteroannulation of benzotriazinones. This newly discovered reactivity of benzotriazinones enables the streamline synthesis of diverse… read more here.
Keywords: ones via; denitrogenative transannulation; transannulation benzotriazinones; dithiol ones ... See more keywords
Enantioselective Synthesis of Functionalized 4-Aryl Hydrocoumarins and 4-Aryl Hydroquinolin-2-ones via Intramolecular Vinylogous Rauhut-Currier Reaction of para-Quinone Methides.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b01331
Abstract: A novel strategy for the asymmetric construction of functionalized 4-aryl-3,4-dihydrocoumarins and 4-aryl-3,4-dihydroquinolin-2-ones via an intramolecular vinylogous Rauhut-Currier reaction of para-quinone methides (p-QMs) under the bifunctional catalysis of chiral amine-phosphine is described. This intramolecular mode for… read more here.
Keywords: vinylogous rauhut; via intramolecular; ones via; rauhut currier ... See more keywords
Preparation of 4-Diazoisoquinolin-3-ones via Dimroth Rearrangement and Their Extension to 4-Aryltetrahydroisoquinolin-3-ones.
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DOI: 10.1021/acs.orglett.9b03708
Abstract: 4-Diazoisoquinolin-3-ones were prepared efficiently via TBAB-promoted rearrangement of 4-diazoisochroman-3-imines under mild reaction conditions. The resulted 4-diazoisoquinolin-3-ones could be conveniently applied for the synthesis of 4-aryltetrahydroisoquinolin-3-ones either by the TfOH-catalyzed reaction with electron-rich arenes or by… read more here.
Keywords: diazoisoquinolin ones; ones via; aryltetrahydroisoquinolin ones; preparation diazoisoquinolin ... See more keywords
Facile assembly of 1,5-diazocan-2-ones via cyclization of tethered sulfonamides to cyclopropenes
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DOI: 10.1039/d0ra09014j
Abstract: The sulfonamide moiety was evaluated as an activating and stabilizing functional group in the metal-templated strain release-driven intramolecular nucleophilic addition of amines to cyclopropenes to generate 1,5-diazocan-2-ones. read more here.
Keywords: via cyclization; assembly diazocan; cyclization tethered; ones via ... See more keywords
Facile access to 2-hydroxy-2-substituted indole-3-ones via a copper-catalyzed oxidative cyclization of 2-arylethynylanilines.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d3cc01390a
Abstract: This paper reports a practical and versatile oxidative cyclization of 2-arylethynylanilines towards 2-hydroxy-2-substituted indol-3-ones via a copper-catalyzed radical approach in the presence of O2. The transformation of 2-hydroxy-2-arylindol-3-ones to 3-hydroxy-3-arylindol-2-ones proceeds well with good yields… read more here.
Keywords: via copper; ones via; hydroxy substituted; oxidative cyclization ... See more keywords
Easy Access to Quinolin-2(1H)-ones via a One-Pot Tandem Oxa-Michael–Aldol Sequence
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DOI: 10.1055/s-0036-1588470
Abstract: An efficient strategy for the synthesis of a variety of quinolin-2(1H)-one derivatives has been developed. The reaction proceeded from cinnamide derivatives via a tandem reaction in the presence of NaOH to afford the corresponding 2-… read more here.
Keywords: easy access; quinolin ones; access quinolin; ones via ... See more keywords