Articles with "ongoing affinity" as a keyword



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Single-Cell Analysis Suggests that Ongoing Affinity Maturation Drives the Emergence of Pemphigus Vulgaris Autoimmune Disease

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Published in 2019 at "Cell reports"

DOI: 10.1016/j.celrep.2019.06.066

Abstract: SUMMARY Pemphigus vulgaris (PV) is an autoimmune disease characterized by blistering sores on skin and mucosal membranes, caused by autoantibodies primarily targeting the cellular adhesion protein, desmoglein-3 (Dsg3). To better understand how Dsg3-specific autoantibodies develop… read more here.

Keywords: pemphigus vulgaris; vulgaris autoimmune; disease; autoimmune disease ... See more keywords