The effects of releasing early results from ongoing clinical trials
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-21116-4
Abstract: Most trials do not release interim summaries on efficacy and toxicity of the experimental treatments being tested, with this information only released to the public after the trial has ended. While early release of clinical… read more here.
Keywords: ongoing clinical; trial; effects releasing; clinical trials ... See more keywords
Neuropathic pain management: a focused review of current treatments and novel data from main ongoing clinical trials
Sign Up to like & getrecommendations! Published in 2025 at "Expert Opinion on Investigational Drugs"
DOI: 10.1080/13543784.2025.2473692
Abstract: ABSTRACT Introduction Neuropathic pain (NP) remains a significant challenge in clinical practice, requiring a sophisticated pharmacotherapeutic strategy for effective symptom management. This review provides a comprehensive analysis of the current pharmacological treatments for NP, focusing… read more here.
Keywords: pain management; review; clinical trials; neuropathic pain ... See more keywords
Early clinical experience using tecovirimat during the 2022 mpox epidemic in Toronto underscores ongoing clinical equipoise and the need for randomized trials
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkaf010
Abstract: Abstract Background Tecovirimat is an antiviral drug that was used compassionately for treating mpox in high-income settings during the 2022 global outbreak. Randomized controlled trials of its efficacy have not yet been completed. Objectives To… read more here.
Keywords: underscores ongoing; tecovirimat; clinical equipoise; ongoing clinical ... See more keywords
Ongoing Clinical Trials in Aging-Related Tissue Fibrosis and New Findings Related to AhR Pathways
Sign Up to like & getrecommendations! Published in 2022 at "Aging and Disease"
DOI: 10.14336/ad.2021.1105
Abstract: Fibrosis is a pathological manifestation of wound healing that replaces dead/damaged tissue with collagen-rich scar tissue to maintain homeostasis, and complications from fibrosis contribute to nearly half of all deaths in the industrialized world. Ageing… read more here.
Keywords: ongoing clinical; clinical trials; trials aging; tissue ... See more keywords
Iran's Approach to COVID-19: Evolving Treatment Protocols and Ongoing Clinical Trials
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Public Health"
DOI: 10.3389/fpubh.2020.551889
Abstract: The coronavirus disease 2019 (COVID-19) pandemic is challenging the health care systems around the world and compelling them to timely share their strategies, tactics and experiences. Since mid-January, a huge volume of instructions has been… read more here.
Keywords: ongoing clinical; approach covid; clinical trials; approach ... See more keywords
The Role of Pharmacotherapy in Treatment of Meningioma: A Systematic Review
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15020483
Abstract: Simple Summary For the last 35 years, various systemic therapies for recurrent or refractory meningiomas have been investigated. The present review aggregated the currently available evidence in the literature regarding the safety and efficacy of… read more here.
Keywords: ongoing clinical; free survival; clinical trials; review ... See more keywords