Articles with "ono 2160" as a keyword



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Hydrolase Activity of the Genetic Variants of Human Alpha-1-Acid Glycoprotein.

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Published in 2022 at "Molecular pharmaceutics"

DOI: 10.1021/acs.molpharmaceut.1c00614

Abstract: In human plasma, the main agent of hydrolysis of the ester-type prodrug of levodopa, designated ONO-2160, is alpha-1-acid glycoprotein (AGP), which is a mixture of the F1*S and A variants at molar ratios of 3:1… read more here.

Keywords: ono 2160; acid glycoprotein; activity; hydrolysis ... See more keywords