Early‐onset Alzheimer's disease shows a distinct neuropsychological profile and more aggressive trajectories of cognitive decline than late‐onset
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51689
Abstract: Early‐ and late‐onset Alzheimer's disease (EOAD and LOAD) share the same neuropathological traits but show distinct cognitive features. We aimed to explore baseline and longitudinal outcomes of global and domain‐specific cognitive function in a well… read more here.
Keywords: alzheimer disease; onset; late onset; onset alzheimer ... See more keywords
PLA2G6-associated late-onset parkinsonism in a Sudanese family.
Sign Up to like & getrecommendations! Published in 2023 at "Annals of clinical and translational neurology"
DOI: 10.1002/acn3.51781
Abstract: INTRODUCTION The phospholipase A2 group VI gene (PLA2G6) encodes an enzyme that catalyzes the hydrolytic release of fatty acids from phospholipids. Four neurological disorders with infantile, juvenile, or early adult-onset are associated with PLA2G6 genetic… read more here.
Keywords: onset parkinsonism; onset; parkinsonism; late onset ... See more keywords
Onset patterns in autism: Variation across informants, methods, and timing
Sign Up to like & getrecommendations! Published in 2018 at "Autism Research"
DOI: 10.1002/aur.1943
Abstract: While previous studies suggested that regressive forms of onset were not common in autism spectrum disorder (ASD), more recent investigations suggest that the rates are quite high and may be under‐reported using certain methods. The… read more here.
Keywords: onset; patterns autism; autism variation; autism ... See more keywords
Clinical correlates of late‐onset versus early‐onset bipolar disorder in a global sample of older adults
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Geriatric Psychiatry"
DOI: 10.1002/gps.5833
Abstract: Late‐onset bipolar disorder (LOBD) represents a significant subgroup of bipolar disorder (BD). However, knowledge for this group is mostly extrapolated from small studies in subjects with early/mixed age of illness onset. In this global sample… read more here.
Keywords: onset bipolar; global sample; onset; bipolar disorder ... See more keywords
Structural signature of classical versus late‐onset friedreich's ataxia by Multimodality brain MRI
Sign Up to like & getrecommendations! Published in 2017 at "Human Brain Mapping"
DOI: 10.1002/hbm.23655
Abstract: Friedreich's ataxia (FRDA) is the most common autosomal‐recessive ataxia worldwide. It is characterized by early onset, sensory abnormalities, and slowly progressive ataxia. However, some individuals manifest the disease after the age of 25 years and… read more here.
Keywords: onset; late onset; friedreich ataxia; ataxia ... See more keywords
Comparison of some biochemical markers between early‐onset and late‐onset colorectal precancerous lesions: A single‐center retrospective study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24637
Abstract: Given that the onset of diseases including colorectal cancer precursors is affecting younger individuals and that obesity is an important risk factor for early‐onset, we conducted a study to explore the biochemical profile of differences… read more here.
Keywords: early onset; onset; onset colorectal; late onset ... See more keywords
Predictability of the rainy season onset date in Central Highlands of Vietnam
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Climatology"
DOI: 10.1002/joc.6383
Abstract: In this study, different criteria to determine the rainy season onset date (RSOD) and its predictability in the Central Highlands (CH) of Vietnam are investigated. Using daily rainfall amounts from 10 meteorological stations for the… read more here.
Keywords: rainy season; season onset; onset; onset date ... See more keywords
Comparison of the efficacy and safety of biologic agents between elderly-onset and young-onset RA patients: the ANSWER cohort study
Sign Up to like & getrecommendations! Published in 2020 at "Rheumatology International"
DOI: 10.1007/s00296-020-04660-y
Abstract: The objective of the study was to compare the efficacy and safety of biological disease-modifying antirheumatic drugs (bDMARDs) between elderly-onset rheumatoid arthritis (EORA) and young-onset rheumatoid arthritis (YORA) patients. Patients with rheumatoid arthritis (RA) aged… read more here.
Keywords: onset; elderly onset; efficacy safety; disease ... See more keywords
Acute disseminated encephalomyelitis associated with debut of a late onset coeliac disease—a case report
Sign Up to like & getrecommendations! Published in 2017 at "Neurological Sciences"
DOI: 10.1007/s10072-017-3207-z
Abstract: Dear Editor, Acute disseminated encephalomyelitis (ADEM) is an immune-medicated condition usually affecting children and younger adults, characterized by multiple demyelinating CNS lesions with a variable presentation of neurological symptoms such as encephalopathy, headache, and different… read more here.
Keywords: onset; late onset; coeliac disease; onset coeliac ... See more keywords
Prevalence and Correlates of Sexual Violence Experienced by Young Adult Black Men Who Have Sex with Men.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of sexual behavior"
DOI: 10.1007/s10508-021-02011-x
Abstract: Men who have sex with men (MSM) experience high prevalence of sexual violence (SV), and SV has well-documented effects on health. Research gaps are especially evident for young Black MSM (YBMSM), who experience significant HIV… read more here.
Keywords: violence; onset; adult; men sex ... See more keywords
Late-onset Pompe disease in France: molecular features and epidemiology from a nationwide study
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Inherited Metabolic Disease"
DOI: 10.1007/s10545-018-0243-7
Abstract: Pompe disease (PD) is caused by a deficiency of lysosomal acid α-glucosidase resulting from mutations in the GAA gene. The clinical spectrum ranges from a rapidly fatal multisystemic disorder (classic PD, onset G mutation was detected… read more here.
Keywords: onset; late onset; epidemiology; nationwide study ... See more keywords