NOX1 Regulates Collective and Planktonic Cell Migration: Insights From Patients With Pediatric-Onset IBD and NOX1 Deficiency.
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DOI: 10.1093/ibd/izaa017
Abstract: BACKGROUND Genetic defects of pediatric-onset inflammatory bowel disease (IBD) provide critical insights into molecular factors controlling intestinal homeostasis. NOX1 has been recently recognized as a major source of reactive oxygen species (ROS) in human colonic… read more here.
Keywords: nox1 deficiency; migration; onset ibd; cell ... See more keywords
Dysregulated inflammasome activity in intestinal inflammation – Insights from patients with very early onset IBD
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DOI: 10.3389/fimmu.2022.1027289
Abstract: Inflammatory bowel disease (IBD) is a multifactorial disorder triggered by imbalances of the microbiome and immune dysregulations in genetically susceptible individuals. Several mouse and human studies have demonstrated that multimeric inflammasomes are critical regulators of… read more here.
Keywords: ibd; early onset; veo ibd; inflammasome activity ... See more keywords
Clinical spectrum of elderly-onset inflammatory bowel disease in India
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DOI: 10.5217/ir.2021.00177
Abstract: Background/Aims Inflammatory bowel disease (IBD) is increasingly being recognized in elderly patients. Data on clinical spectrum of elderly-onset IBD patients is lacking from India. Methods A cross-sectional retrospective analysis of a prospectively maintained database of… read more here.
Keywords: spectrum elderly; disease; clinical spectrum; elderly onset ... See more keywords