Childhood-onset lupus nephritis is characterized by complex interactions between kidney stroma and infiltrating immune cells.
Sign Up to like & getrecommendations! Published in 2024 at "Science translational medicine"
DOI: 10.1126/scitranslmed.adl1666
Abstract: Children with systemic lupus erythematosus (SLE) are at increased risk of developing kidney disease, termed childhood-onset lupus nephritis (cLN). Single-cell transcriptomics of dissociated kidney tissue has advanced our understanding of LN pathogenesis, but loss of… read more here.
Keywords: onset lupus; lupus nephritis; cell; infiltrating immune ... See more keywords
Outcomes in juvenile onset lupus: single center cohort from a developing country
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DOI: 10.1177/0961203318791046
Abstract: Introduction About 10–20% of systemic lupus erythematosus (SLE) patients have onset in childhood and have more severe organ involvement. Survival of juvenile SLE patients is improving worldwide. Long-term data of childhood onset SLE from developing… read more here.
Keywords: single center; lupus single; disease; outcomes juvenile ... See more keywords
Worse Renal Presentation and Prognosis in Initial-Onset Lupus Nephritis than Early-Onset Lupus Nephritis
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DOI: 10.3349/ymj.2020.61.11.951
Abstract: Purpose To compare the clinical characteristics and renal outcomes between patients who initially had lupus nephritis (LN) at the onset of systemic lupus erythematosus (SLE) (initial-onset LN) and those who developed LN within 5 years… read more here.
Keywords: onset; early onset; initial onset; lupus nephritis ... See more keywords