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   Articles with "onset multiple" as a keyword



Effect of Dimethyl Fumarate vs Interferon β-1a in Patients With Pediatric-Onset Multiple Sclerosis

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recommendations! Published in 2022 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2022.30439

Abstract: This randomized clinical trial investigates the efficacy and safety of dimethyl fumarate vs interferon β-1a for treatment of pediatric-onset multiple sclerosis. read more here.

Keywords: onset multiple; pediatric onset; multiple sclerosis; dimethyl fumarate ... See more keywords
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miRNA contributions to pediatric‐onset multiple sclerosis inferred from GWAS

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recommendations! Published in 2019 at "Annals of Clinical and Translational Neurology"

DOI: 10.1002/acn3.786

Abstract: Onset of multiple sclerosis (MS) occurs in childhood for approximately 5% of cases (pediatric MS, or ped‐MS). Epigenetic influences are strongly implicated in MS pathogenesis in adults, including the contribution from microRNAs (miRNAs), small noncoding… read more here.

Keywords: contributions pediatric; mirna contributions; multiple sclerosis; onset multiple ... See more keywords

Impaired remyelination in late-onset multiple sclerosis

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recommendations! Published in 2025 at "Acta Neuropathologica"

DOI: 10.1007/s00401-025-02868-5

Abstract: A reduced regenerative capacity may contribute to faster disease progression and poorer relapse recovery in multiple sclerosis patients with disease onset after the age of 50, a condition known as late-onset multiple sclerosis (LOMS). We… read more here.

Keywords: multiple sclerosis; late onset; onset multiple; remyelination ... See more keywords

Newer Treatment Approaches in Pediatric-Onset Multiple Sclerosis

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recommendations! Published in 2019 at "Current Treatment Options in Neurology"

DOI: 10.1007/s11940-019-0592-z

Abstract: With the recognition that pediatric-onset multiple sclerosis (POMS) is characterized by more prominent disease activity, earlier age at onset of disability milestones, and more prominent cognitive impairment compared with physical disability earlier in the disease… read more here.

Keywords: treatment; multiple sclerosis; treatment approaches; onset multiple ... See more keywords
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Recent Onset of Multiple Asymptomatic Brownish Papules.

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recommendations! Published in 2019 at "Actas dermo-sifiliograficas"

DOI: 10.1016/j.ad.2018.06.029

Abstract: Dermoscopy revealed a homogeneous clear brown area with a delicate pigment network (Fig. 2A). High-frequency ultrasound (18 MHz, MyLab 25Gold, Esaote) revealed well-defined oval lesions in the superficial dermis. These were slightly hypoechogenic with respect… read more here.

Keywords: brownish papules; multiple asymptomatic; recent onset; asymptomatic brownish ... See more keywords
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Paediatric onset of multiple sclerosis: Analysis of chemokine and cytokine levels in the context of the early clinical course.

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recommendations! Published in 2020 at "Multiple sclerosis and related disorders"

DOI: 10.1016/j.msard.2020.102467

Abstract: BACKGROUND Inflammatory activity in children with paediatric onset multiple sclerosis (POMS) is higher than that in adults with MS. Chemokine/cytokine profiling in children may provide new insights into the disease pathogenesis and clinical course. The… read more here.

Keywords: sclerosis; paediatric onset; time; course ... See more keywords

COVID-19 in a temporal relation to the onset of multiple sclerosis

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recommendations! Published in 2021 at "Multiple Sclerosis and Related Disorders"

DOI: 10.1016/j.msard.2021.102863

Abstract: Neurological complications of COVID-19 have been described. We present the case of a 27-year-old woman who developed COVID-19 in April 2020. She continued to present anosmia and ageusia eight months later. Six months after contracting… read more here.

Keywords: sclerosis; temporal relation; relation onset; multiple sclerosis ... See more keywords

Update on pediatric-onset multiple sclerosis.

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recommendations! Published in 2018 at "Revue neurologique"

DOI: 10.1016/j.neurol.2018.04.003

Abstract: Pediatric-onset multiple sclerosis (POMS) has distinctive features compared with adult-onset multiple sclerosis (AOMS), and warrants caution despite being a rare form of MS. POMS diagnostic criteria are somewhat different from those used in AOMS, with… read more here.

Keywords: multiple sclerosis; onset multiple; pediatric onset; update pediatric ... See more keywords

Clinical utility of brief screening measures during neuropsychological consultation for pediatric onset multiple sclerosis

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recommendations! Published in 2024 at "Journal of the International Neuropsychological Society"

DOI: 10.1017/s1355617724000419

Abstract: Abstract Objective: Pediatric-onset multiple sclerosis (POMS) accounts for approximately 2 to 5% of all individuals with MS and is associated with an increased risk for cognitive impairment. In recent years, neuropsychological screening questionnaires have been… read more here.

Keywords: pediatric onset; multiple sclerosis; clinical utility; onset multiple ... See more keywords

B – 58 Optimizing Cognitive Monitoring for Pediatric-Onset Multiple Sclerosis via Data-Tracking Dashboards

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recommendations! Published in 2025 at "Archives of Clinical Neuropsychology"

DOI: 10.1093/arclin/acaf084.208

Abstract: Over 30% of youth with pediatric-onset multiple sclerosis (POMS) experience cognitive impairment, making timely identification and neuropsychological screening essential (Kalb et al., 2018). Best practice recommends baseline assessment and annual reevaluations (Kalb et al., 2018;… read more here.

Keywords: pediatric onset; cognitive monitoring; multiple sclerosis; onset multiple ... See more keywords

Late‐onset multiple system atrophy: Neuropathological features associated with slow disease progression

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recommendations! Published in 2025 at "Brain Pathology"

DOI: 10.1111/bpa.70016

Abstract: Patients with late‐onset (LO) multiple system atrophy (MSA), whose initial symptoms appear at age 75 years or older, are more common than previously assumed, but their clinicopathological characteristics remain unclear. We aimed to clarify the clinicopathological… read more here.

Keywords: disease; late onset; msa; onset multiple ... See more keywords