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Published in 2018 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.3450
Abstract: Pseudohypoparathyroidism type 1A (PHP1A), pseudoPHP (PPHP), and PHP type 1B (PHP1B) are caused by maternal and paternal GNAS mutations and abnormal methylation at maternal GNAS promoter(s), respectively. Adult PHP1A patients are reportedly obese and short,…
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Keywords:
growth;
onset obesity;
early onset;
php1a ... See more keywords
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Published in 2017 at "Biochimie"
DOI: 10.1016/j.biochi.2017.05.019
Abstract: The modulation of the intestinal microbiota by high-fat diet (HFD) has a major impact on both immunological and metabolic functions of the host. Taking this into consideration, the aim of this contribution is to review…
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Keywords:
physiology;
high fat;
onset obesity;
intestinal microbiota ... See more keywords
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Published in 2021 at "Stem cell research"
DOI: 10.1016/j.scr.2021.102432
Abstract: Aryl hydrocarbon receptor nuclear translocator 2 (ARNT2) is a basic helix-loop-helix (bHLH/PAS) transcription factor involved in the development of paraventricular nucleus of the hypothalamus (PVH) through the heterodimerization with Single-minded 1 (SIM1) (Michaud et al.,…
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Keywords:
line cuimci003;
early onset;
onset obesity;
ipsc line ... See more keywords
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Published in 2021 at "Clinical and Experimental Hypertension"
DOI: 10.1080/10641963.2021.1883049
Abstract: ABSTRACT Objective: To explore the role of resistin in the onset and development of obesity-related hypertension. Methods: Resistin serum levels were tested by ELISA in 153 adult subjects among four characteristic Chinese adult physical examination…
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Keywords:
onset obesity;
blood;
hypertension;
role resistin ... See more keywords
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Published in 2022 at "Childhood obesity"
DOI: 10.1089/chi.2022.0089
Abstract: Background: Severe early-onset childhood obesity is diagnosed by having a BMI >120% of the 95th percentile before age 5 years. Treatment for early-onset obesity is frequently unsuccessful. Prior studies have shown parents of children with…
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Keywords:
isolation sea;
sea experts;
children early;
early onset ... See more keywords
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Published in 2022 at "Transplantation"
DOI: 10.1097/tp.0000000000004222
Abstract: Background. Lung transplant (LTx) recipients who gain weight after transplantation may experience an upward shift in body mass index (BMI) that places them in the obese category. The incidence, risk factors, and impact on metabolic…
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Keywords:
ltx;
new onset;
risk;
bmi ... See more keywords
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Published in 2022 at "Obesity Facts"
DOI: 10.1159/000524941
Abstract: Introduction: The psychosocial background of subjects with severe obesity developed from childhood onset obesity (CO) and their outcomes after bariatric surgery have not been fully investigated. Methods: 305 subjects were enrolled in the J-SMART study,…
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Keywords:
laparoscopic sleeve;
group;
childhood onset;
obesity ... See more keywords
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Published in 2017 at "Journal of Pediatric Endocrinology and Metabolism"
DOI: 10.1515/jpem-2016-0435
Abstract: Abstract Background: Obesity is genetically heterogeneous and highly heritable, although polymorphisms explain the phenotype in only a small proportion of obese children. We investigated the presence of copy number variations (CNVs) in “classical” genes known…
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Keywords:
copy number;
early onset;
onset obesity;
number variations ... See more keywords
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Published in 2020 at "Journal of Pediatric Endocrinology and Metabolism"
DOI: 10.1515/jpem-2020-0111
Abstract: Abstract Objectives Rapid-onset obesity with hypoventilation, hypothalamic dysfunction, and autonomic dysregulation (ROHHAD) is a rare, potentially fatal, pediatric syndrome. Case presentations We describe three cases of ROHHAD-syndrome in Greece. The main and earliest symptom was…
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Keywords:
rohhad syndrome;
onset obesity;
syndrome still;
cases rohhad ... See more keywords
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Published in 2022 at "Journal of Pediatric Endocrinology and Metabolism"
DOI: 10.1515/jpem-2021-0756
Abstract: Abstract Objectives Genetic factors have a key role in childhood obesity with higher rates in children than adults. Among the monogenic types of non-syndromic obesity, melanocortin-4 receptor (MC4R) deficiency is the most frequent cause. Beside…
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Keywords:
mc4r gene;
early onset;
variants polymorphisms;
obesity ... See more keywords
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Published in 2022 at "Molecular and Cellular Endocrinology"
DOI: 10.2139/ssrn.4031362
Abstract: Loss-of-function mutations in melanocortin-4 receptor (MC4R) are the most common cause of monogenic obesity, a severe type of early-onset obesity. Our aim was to determine the prevalence of MC4R mutations in a cohort of 97…
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Keywords:
mc4r mutations;
early onset;
obesity;
onset obesity ... See more keywords