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Published in 2018 at "Cancer cell"
DOI: 10.1016/j.ccell.2018.11.010
Abstract: In this issue of Cancer Cell, Gerhauser et al. analyze early-onset prostate cancers, showing roles for androgen receptor-driven rearrangements, an early APOBEC-driven mutational mechanism, and ESRP1 gene duplication. Through integration of whole-genome, transcriptome, and methylome data,…
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Keywords:
cancer;
early onset;
onset prostate;
evolution ... See more keywords
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Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.826778
Abstract: Objective To investigate the inherited mutations and their association with clinical features and treatment response in young-onset prostate cancer patients. Method Targeted gene sequencing on 139 tumor susceptibility genes was conducted with a total of…
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Keywords:
early onset;
germline mutations;
onset prostate;
prostate cancer ... See more keywords
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Published in 2022 at "Journal of the National Comprehensive Cancer Network : JNCCN"
DOI: 10.6004/jnccn.2022.7010
Abstract: BACKGROUND The aim of this study was to compare the risks of new-onset prostate cancer between metformin and sulfonylurea users with type 2 diabetes mellitus (T2DM). METHODS This population-based retrospective cohort study included male patients…
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Keywords:
prostate cancer;
new onset;
sulfonylurea;
onset prostate ... See more keywords