Articles with "onset prostate" as a keyword



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Initiation and Evolution of Early Onset Prostate Cancer.

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Published in 2018 at "Cancer cell"

DOI: 10.1016/j.ccell.2018.11.010

Abstract: In this issue of Cancer Cell, Gerhauser et al. analyze early-onset prostate cancers, showing roles for androgen receptor-driven rearrangements, an early APOBEC-driven mutational mechanism, and ESRP1 gene duplication. Through integration of whole-genome, transcriptome, and methylome data,… read more here.

Keywords: cancer; early onset; onset prostate; evolution ... See more keywords
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Germline Mutations in Patients With Early-Onset Prostate Cancer

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.826778

Abstract: Objective To investigate the inherited mutations and their association with clinical features and treatment response in young-onset prostate cancer patients. Method Targeted gene sequencing on 139 tumor susceptibility genes was conducted with a total of… read more here.

Keywords: early onset; germline mutations; onset prostate; prostate cancer ... See more keywords
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Risk of New-Onset Prostate Cancer for Metformin Versus Sulfonylurea Use in Type 2 Diabetes Mellitus: A Propensity Score-Matched Study.

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Published in 2022 at "Journal of the National Comprehensive Cancer Network : JNCCN"

DOI: 10.6004/jnccn.2022.7010

Abstract: BACKGROUND The aim of this study was to compare the risks of new-onset prostate cancer between metformin and sulfonylurea users with type 2 diabetes mellitus (T2DM). METHODS This population-based retrospective cohort study included male patients… read more here.

Keywords: prostate cancer; new onset; sulfonylurea; onset prostate ... See more keywords